resources AND FAQs

neffy 2 mg is a nasal spray used to treat life-threatening, allergic emergencies including anaphylaxis, in adults and children who weigh 66 lbs or more (30 kg or more), who are at risk for or have a history of serious allergic emergencies. Please see full Prescribing Information and Patient Information for neffy.

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neffy is the first-and-only needle-free epinephrine nasal spray for serious allergic reactions.

Learn More about neffy.

The neffy nasal spray device is compact and designed for easy carrying, so treatment is always close at hand. It is about the size of a car key, measuring 2.25”H X 1.75”W X .75”D.

Explore the neffy Interactive 3D Model.

Use neffy as soon as you notice symptoms of a serious allergic reaction, and follow these four steps:

1. REMOVE

Remove neffy from packaging. Pull open the packaging to remove the neffy nasal spray device.

2. HOLD

Hold device as shown. Hold the device with your thumb on the bottom of the plunger and a finger on either side of the nozzle.

• Do not pull or push on the plunger.

• Do not test or prime (pre-spray). Each device has only 1 spray.

3. INSERT

Insert the nozzle into a nostril until your fingers touch your nose. Keep the nozzle straight into the nose pointed toward your forehead.

• Do not point (angle) the nozzle to the nasal septum (wall between your 2 nostrils) or outer wall of the nose.

4. PRESS

Press plunger up firmly until it snaps up and sprays liquid into the nostril.

• Do not sniff during or after the dose is given. If any liquid drips out of the nose, you may need to give a second dose of neffy after checking for symptoms.

When using neffy:

• Each neffy nasal spray device has only 1 dose of medicine and is for single-use only.
• Always keep 2 neffy nasal spray devices with you.
• Use only in the nose. Avoid spraying in the eyes or mouth.
• Do not angle nozzle.
• Do not sniff during or after use.
• It is recommended that right‑handed dosing should be to the right nostril and left‑handed dosing should be to the left nostril.
• Patient can be in any position (e.g. sitting, standing, laying, reclining).

After using neffy:

• Get emergency medical help for further treatment of the allergic emergency (anaphylaxis), if needed, after using neffy.
• Check for symptoms after the first dose of neffy. If symptoms get worse or come back, give a second dose of neffy in the SAME nostril starting 5 minutes after the first dose.

Check your neffy periodically to be sure the expiration date has not passed. Replace your neffy before the expiration date has passed.

To learn more, read the full Instructions for Use.

Watch How to Use Videos.

Each single-use neffy device contains one dose of epinephrine and comes in a blister pack. Your prescription comes with two devices, in case a second dose is needed.

Learn more about neffy Storage and Handling.

You don’t have to wait for your current epinephrine needle-injector prescription to expire to get neffy. Ask your doctor for neffy today.

Find out how to get neffy delivered to your doorstep.

Yes. If you have a neffy prescription, then you can sign up for expiration reminders for up to 4 devices.

Sign Up for neffy Expiration Reminders.

Side effects of neffy may include throat irritation, tingling nose, headache, nasal discomfort, feeling over excitement, nervousness or anxiety, tingling sensation, fatigue, shakiness, runny nose, itchy nose, sneezing, stomach pain, pain in gums of teeth, numbness in the mouth, nasal congestion, dizziness, nausea, and vomiting.

See full Prescribing Information and Patient Information for a complete list of side effects.

Talk to your doctor before using other nasal sprays within 2 weeks of using neffy.

neffy delivers the same epinephrine you'd get from a needle-injector, but it comes in a nasal spray.

The epinephrine in neffy affects the body like the epinephrine in a needle-injector, including blood pressure and heart rate.

Learn more about How neffy Works.

The epinephrine in neffy is designed to be rapidly absorbed into the nasal passage to reverse the reaction. neffy uses Intravail^® technology, which temporarily loosens the spaces between the nasal cells to help epinephrine be absorbed into the body.

Learn more about How neffy Works.

The nasal spray can get through stuffy noses, so don’t hesitate to use it in these conditions.

Store neffy at room temperature between 68°F to 77°F (20°C to 25°C). Storage of neffy at high temperatures up to 122°F (50° C) is allowed for a few days.

Learn more about neffy Storage and Handling.

Do not freeze. If neffy freezes, the device will not spray.

Learn more about neffy Storage and Handling.

The epinephrine in neffy lasts for 30 months. The expiration date can be found on the back of each device on the black label. Be sure to check the expiration date periodically and replace before the expiration date.

Sign Up for neffy Expiration Reminders.

Eligible patients^* with commercial insurance can get neffy for as little as $25 with a co‑pay card.

Learn more about the co‑pay program.

^*Terms and Conditions apply.

Explore more savings and support options.

If you have commercial insurance, you may qualify for help with paying deductibles, co-pays, and co-insurance for each neffy prescription. With the neffy co-pay savings program, pay as little as $25 if eligible^*

Learn More.

^*Terms and Conditions apply.

There are various reasons why your insurance carrier may not cover your neffy prescription, such as missing or incorrect information.

You can contact neffyconnect at 1‑877‑MY‑NEFFY (1‑877‑696‑3339).