For U.S. Residents Only
Prescribing InformationPrescribing InfoPatient InformationPatient InfoInstructions for UseInstructions for Use

HOW TO USE neffy

Not actual size.
Keep neffy with its instructions until ready to use.

HERE'S HOW TO USE neffy IN FOUR STEPS

Use neffy as soon as you notice symptoms of a serious allergic reaction.

1. REMOVE

Remove neffy from packaging. Pull open the packaging to remove the neffy nasal spray device.

2. HOLD

Hold device as shown. Hold the device with your thumb on the bottom of the plunger and a finger on either side of the nozzle.

  • Do not pull or push on the plunger.
  • Do not test or prime (pre-spray). Each device has only 1 spray.

3. INSERT

Insert the nozzle into a nostril until your fingers touch your nose. Keep the nozzle straight into the nose pointed toward your forehead.

  • Do not point (angle) the nozzle to the nasal septum (wall between your 2 nostrils) or outer wall of the nose.

4. PRESS

Press plunger up firmly until it snaps up and sprays liquid into the nostril.

  • Do not sniff during or after the dose is given. If any liquid drips out of the nose, you may need to give a second dose of neffy after checking for symptoms.

WHEN USING neffy:

  • Each neffy nasal spray device has only 1 dose of medicine and is for single-use only.
  • Always carry 2 neffy nasal spray devices with you.
  • Use only in the nose. Avoid spraying in the eyes or mouth.
  • Do not angle nozzle.
  • Do not sniff during or after use.
  • It is recommended that right‑handed dosing should be to the right nostril and left‑handed dosing should be to the left nostril.
  • Patient can be in any position (e.g. sitting, standing, laying, reclining).

AFTER USING neffy:

Get emergency medical help for further treatment of the allergic emergency (anaphylaxis), if needed, after using neffy. Tell them that a neffy nasal spray has been used.

Check for symptoms after the first dose of neffy. If symptoms get worse or come back, give a second dose of neffy in the SAME nostril starting 5 minutes after the first dose.

Check your neffy periodically to be sure the expiration date has not passed. Replace your neffy before the expiration date has passed.

To learn more, read the full Instructions for Use.

DOWNLOAD

HOW‑TO‑USE VIDEOS

Watch these videos to learn how to use neffy.

In an Adult

In an Adolescent

PLAN AHEAD
WITH neffy

Complete the step-by-step neffy Action Plan—it can help inform others of known allergens and how to properly use neffy on you or your child during a serious allergic reaction.

DOWNLOAD
Not actual size.

questions? CHECK OUT OUR FAQs PAGE

Here you will find answers to common questions about neffy.

GET ANSWERS

WHAT IS neffy?

neffy 2 mg is a nasal spray used to treat life-threatening, allergic emergencies including anaphylaxis, in adults and children who weigh 66 lbs or more (30 kg or more), who are at risk for or have a history of serious allergic emergencies.

IMPORTANT SAFETY INFORMATION

What is the most important information that I should know about neffy?

neffy contains epinephrine, a medicine used to treat allergic emergencies (anaphylaxis). Anaphylaxis can be life-threatening, can happen in minutes, and can be caused by stinging and biting insects, allergy injections, foods, medicines, exercise, or other unknown causes.

Always carry two neffy nasal sprays with you because you may not know when anaphylaxis may happen and because you may need a second dose of neffy if symptoms continue or come back. neffy is for use in the nose only.

Use neffy right away, as soon as you notice symptoms of an allergic reaction. If symptoms continue or get worse after the first dose of neffy, a second dose is needed. If needed, administer a second dose using a new neffy in the same nostril starting 5 minutes after the first dose. Get emergency medical help for further treatment of the allergic emergency (anaphylaxis), if needed after using neffy.

Tell your healthcare provider if you have underlying structural or anatomical nasal conditions, all the medicines you take, and about all your medical conditions, especially if you have heart problems, kidney problems, low potassium in your blood, Parkinson's disease, thyroid problems, high blood pressure, diabetes, are pregnant or plan to become pregnant, or plan to breastfeed.

Tell your healthcare provider if you take or use other nasal sprays or water pills (diuretics) or if you take medicines to treat depression, abnormal heart beats, Parkinson's disease, heart disease, thyroid disease, medicines used in labor, and medicines to treat allergies. neffy and other medications may affect each other, causing side effects. neffy may affect the way other medicines work, and other medicines may affect how neffy works.

What are the side effects of neffy?

neffy may cause serious side effects. If you have certain medical conditions or take certain medicines, your condition may get worse, or you may have more or longer lasting side effects when you use neffy.

Side effects of neffy may include throat irritation, tingling nose, headache, nasal discomfort, feeling over excitement, nervousness or anxiety, tingling sensation, fatigue, shakiness, runny nose, itchy nose, sneezing, stomach pain, pain in gums of teeth, numbness in the mouth, nasal congestion, dizziness, nausea, and vomiting.

Tell your healthcare provider if you have any side effects that bother you or that do not go away after using neffy.

These are not all of the possible side effects of neffy. Call your healthcare provider for medical advice about side effects. To report side effects, contact ARS Pharmaceuticals Operations, Inc. at 1-877-MY-NEFFY (877-696-3339) or the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please see the full Prescribing Information and Patient Information for neffy.

References

  1. neffy [package insert], 08/2024; ARS Pharmaceuticals Operations, Inc.

WHAT IS neffy?

neffy 2 mg is a nasal spray used to treat life-threatening, allergic emergencies including anaphylaxis, in adults and children who weigh 66 lbs or more (30 kg or more), who are at risk for or have a history of serious allergic emergencies.

IMPORTANT SAFETY INFORMATION

What is the most important information that I should know about neffy?

neffy contains epinephrine, a medicine used to treat allergic emergencies (anaphylaxis). Anaphylaxis can be life-threatening, can happen in minutes, and can be caused by stinging and biting insects, allergy injections, foods, medicines, exercise, or other unknown causes.

Always carry two neffy nasal sprays with you because you may not know when anaphylaxis may happen and because you may need a second dose of neffy if symptoms continue or come back. neffy is for use in the nose only.

Use neffy right away, as soon as you notice symptoms of an allergic reaction. If symptoms continue or get worse after the first dose of neffy, a second dose is needed. If needed, administer a second dose using a new neffy in the same nostril starting 5 minutes after the first dose. Get emergency medical help for further treatment of the allergic emergency (anaphylaxis), if needed after using neffy.

Tell your healthcare provider if you have underlying structural or anatomical nasal conditions, all the medicines you take, and about all your medical conditions, especially if you have heart problems, kidney problems, low potassium in your blood, Parkinson's disease, thyroid problems, high blood pressure, diabetes, are pregnant or plan to become pregnant, or plan to breastfeed.

Tell your healthcare provider if you take or use other nasal sprays or water pills (diuretics) or if you take medicines to treat depression, abnormal heart beats, Parkinson's disease, heart disease, thyroid disease, medicines used in labor, and medicines to treat allergies. neffy and other medications may affect each other, causing side effects. neffy may affect the way other medicines work, and other medicines may affect how neffy works.

What are the side effects of neffy?

neffy may cause serious side effects. If you have certain medical conditions or take certain medicines, your condition may get worse, or you may have more or longer lasting side effects when you use neffy.

Side effects of neffy may include throat irritation, tingling nose, headache, nasal discomfort, feeling over excitement, nervousness or anxiety, tingling sensation, fatigue, shakiness, runny nose, itchy nose, sneezing, stomach pain, pain in gums of teeth, numbness in the mouth, nasal congestion, dizziness, nausea, and vomiting.

Tell your healthcare provider if you have any side effects that bother you or that do not go away after using neffy.

These are not all of the possible side effects of neffy. Call your healthcare provider for medical advice about side effects. To report side effects, contact ARS Pharmaceuticals Operations, Inc. at 1-877-MY-NEFFY (877-696-3339) or the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please see the full Prescribing Information and Patient Information for neffy.

References

  1. neffy [package insert], 08/2024; ARS Pharmaceuticals Operations, Inc.